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Sophie Layé obtient la labellisation Fondation pour la Recherche Médicale (FRM) de son équipe pour étudier les mécanismes neuroprotecteurs des acides gras polyinsaturés dans la dépression.

Neuroprotective mechanisms of n-3 polyunsaturated fatty acids in depression (PRINSS)

Equipe rattachée à NutriNeuro

Depression affects about 350 million people/year and represents the first leading cause of disability worldwide. Recently, a considerable attention has been paid to n-3 polyunsaturated fatty acids (PUFAs) in the pathophysiology of mood disorders. The purpose of the PRINSS project is to examine how n-3 PUFAs protect from protracted changes in synaptic functions, brain circuits and emotional behavior in a mouse model of depression using electrophysiological, optical, optogenetic and behavioral methods.

Contact: Sophie Layé, tél: 05 57 57 92 18 - mél: sophie.laye@inra.fr